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Sponsored Research and Scholarly Activity
Research
  
The list below includes active faculty projects with extramural funding. Those with "CCDA"in the Sponsor column are currently being conducted with support through the Osteopathic Heritage Foundation endowment. For additional information on a faculty member's interests, please follow the link to their departmental Web page.


Principal Investigator
Sponsor
Project Title
C. Adams, Ph.D.

NIH (subcontract)



NIH (subcontract) 

 
CCDA

Creating an infection-free intraosseous transcutaneous amputation prosthesis

 

A new allograft that promotes long-term, infection-free skeletal repair

 

Effect of liposuction technique on the validity and differentiation of adipose derived stem cell

D. Appelt, Ph.D.

Penna. Dept. of Health

 Dissecting the apoptosis pathway affected by C. pneumoniae in Alzheimer's disease
Y. Bai, Ph.D. CCDA Nerve growth factors intranasal delivery to the CNS for Alzheimer’s disease treatment
B. Balin, Ph.D.

Osteopathic Heritage Foundation

CCDA
Endowment for Aging Research
 
 
 
The role of tryptophan metabolism in C. pneumoniae infected monocytes: Implications for Alzheimer’s disease
R. Barsotti, Ph.D. NIH Determinants of cardiac thin filament regulation
R. Borghaei, Ph.D.
NIH
 
 
 
CCDA
IL-1 regulation of MMP-1 and MMP-3 genes in gingival and synovial fibroblasts
 
Effects of nicotine and glucose on production of inflammatory mediators in response to IL-1 and LPS in human gingival fibroblasts and CAL27 oral cancer cells

B. Buxton, Ph.D.
(Georgia campus)

Pearson Benjamin Cummings

Interactive CD-ROM on the immune system for undergraduate physiology textbooks

Q. Chen, Ph.D. CCDA The oxidative stress and inflammatory responses under acute hypoglycemic conditions
M. D'Angelo, Ph.D. CCDA Novel metalloprotease peptide derivative therapeutics for osteoarthritis
R. DiTomasso, Ph.D. Pew Charitable Trusts Enhancing behavioral health service delivery for vulnerable adults at the PCOM Healthcare Centers
S. Felgoise, Ph.D.

Christopher Reeve Paralysis Foundation

Penna. Dept. of Health

Measuring quality of life in individuals with amyotrophic lateral sclerosis

Psychological functioning, coping, and factors affecting quality of life in persons with long QT syndrome

K. Galluzzi, D.O.

CCDA



Medical College of Wisconsin

The physician's role in death: Utilizing the SP program to bring issues to life

Medical School Palliative Care Education Project

S. Hingley, Ph.D.

Penna. Dept. of Health


CCDA

Entry mechanisms of mouse hepatitis virus, a model for multiple sclerosis

Changes in expression of genes associated with Alzheimer’s disease and β-amyloid processing due to infection of neuronal cells by C. pneumoniae and/or herpes simplex virus type I

P. Kottsieper, Ph.D. NIH (subcontract)

Adherence and empowerment:  Service participation and meaningful outcomes

M. Kuchera, D.O.
Philadelphia Health Care Trust; Herb & Karen Lotman Foundation
 
 
 
American Osteopathic Association
 
 
Function, quality of life, and possible mechanisms of action in the adjunctive care of patients with Parkinson's Dseae treated with whole body, periodic acceleration &/or OMT: Pilot studies
 

High-tech/high-touch translational care for MS: Integrating OMT, periodic acceleration therapy and TMR with IsoPUMP® maximal effort exercise

C.S. Little, Ph.D.

Pennsylvania Department of Community and Economic Development

Immune modulation of T-cells from peanut-sensitized inbred mice

H. Lu, Ph.D.
(Georgia campus)		 CCDA Optogenic study of cerebellar circuit
E. Mochan, Ph.D., D.O.
Edna G. Kynett Memorial Foundation
 
HRSA
Self-management program to prevent cardiovascular disease
 
 

Establishing a predoctoral collaborative center for enhancing interest in primary care practice

H. Parihar, R.Ph., Ph.D.
(Georgia campus)		 CCDA Design and synthesis of molecular probes for serotonin type 3 receptors and nicotinic acetylcholine receptor architecture and molecular-level function
A. Sharma, Pharm.D., Ph.D.
(Georgia campus)

Oral and Maxillofacial Surgery Foundation (subcontract)

CCDA

Low-dose ketamine (intraoperative) decreases postoperative opioid use

 

 

 

Ketamine-mediated modulation of NMDA and opioid receptors in activated platelets

D. Wang, Ph.D.
(Georgia campus)		 CCDA Dually targeting L-type Ca2+ channel and type 4 phosphodiesterase for treatment of obesity
M. Xu, M.D., Ph.D. CCDA Axon regeneration
L. Young, Ph.D.







 NIH



CCDA		 In vivo and ex vivo mechanisms related to eNOS uncoupling during reperfusion

Tetrahydrobiopterin (BH4) and dihydrobiopterin (BH2) in leukocyte-endothelium interactions using intravital microscopy
D. Zhang, Ph.D.
Penna. Dept. of Health
Role of nutrition in prostate cance